Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6878188 | 1.00 | BCHE (0.46) | BCHEACHEAPPCYP1A2CYP3A4 | |
| SCHEMBL6876922 | 0.94 | BCHE (0.41) | BCHEACHEAPPCYP1A2CYP3A4 | |
| SCHEMBL6464230 | 0.94 | BCHE (0.41) | BCHEACHEAPPCYP1A2CYP3A4 | |
| SCHEMBL6875579 | 0.94 | MCHR1 (0.42) | BCHEACHEAPPCYP1A2CYP3A4 | |
| SCHEMBL6875570 | 0.94 | MCHR1 (0.42) | BCHEACHEAPPCYP1A2CYP3A4 | |
| SCHEMBL6876919 | 0.91 | MCHR1 (0.41) | BCHEACHEAPPADRA2ANPY5R | |
| SCHEMBL6877060 | 0.91 | MCHR1 (0.41) | BCHEACHEAPPADRA2ANPY5R | |
| SCHEMBL6877050 | 0.91 | MCHR1 (0.41) | BCHEACHEAPPADRA2ANPY5R | |
| SCHEMBL6876906 | 0.91 | MCHR1 (0.41) | BCHEACHEAPPADRA2ANPY5R | |
| SCHEMBL6878131 | 0.88 | MCHR1 (0.44) | BCHEACHEAPPADRA2ANPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |