Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 5/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686808 | 0.91 | CTSA (0.42) | CTSAPTGER3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL686624 | 0.86 | MEN1 (0.42) | CTSAMAPTALDH1A1TP53RXFP1 | |
| SCHEMBL688193 | 0.86 | CTSA (0.39) | CTSAMAPTSMN1; SMN2RXFP1 | |
| SCHEMBL686663 | 0.85 | PTGER3 (0.44) | CTSAPTGER3MAPT | |
| SCHEMBL687120 | 0.85 | MEN1 (0.42) | CTSAPTGER3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL687331 | 0.85 | MEN1 (0.41) | CTSAPTGER3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL688313 | 0.85 | MEN1 (0.42) | CTSAPTGER3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL687079 | 0.84 | PTGER3 (0.43) | CTSAPTGER3MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL686806 | 0.83 | PTGER3 (0.45) | CTSAPTGER3MAPT | |
| SCHEMBL688029 | 0.83 | CTSA (0.42) | CTSAPTGER3MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |