Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.31 |
| ▸ | ITGAV | P06756 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL686618 | 0.91 | KMT2A (0.37) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL686719 | 0.91 | MEN1 (0.38) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL688414 | 0.91 | KMT2A (0.37) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL686692 | 0.89 | SMN1; SMN2 (0.36) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL687167 | 0.89 | KMT2A (0.37) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL686619 | 0.88 | KMT2A (0.35) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL687480 | 0.88 | CTSA (0.36) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL688098 | 0.88 | MEN1 (0.45) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL688359 | 0.87 | KMT2A (0.35) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL686894 | 0.87 | FFAR1 (0.38) | KMT2AMEN1SMN1; SMN2ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |