SCHEMBL6879149

SCHEMBL6879149

O=Cc1nn(Cc2cc(-c3ccc(Cl)s3)on2)c2ccccc12

nearest known ligand 0.55

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.55
F2 P00734 4/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4415805 0.82 F10 (0.43) F10F2
SCHEMBL4412919 0.82 F10 (0.65) F10F2
SCHEMBL4420400 0.81 F10 (0.51) F10F2
SCHEMBL6017015 0.73 F10 (0.57) F10F2
SCHEMBL3969893 0.72 F10 (0.65) F10F2
SCHEMBL5730214 0.71 F10 (0.52) F10F2
SCHEMBL3968182 0.71 F10 (0.66) F10F2
SCHEMBL1674990 0.71 F10 (0.66) F10F2
SCHEMBL4425775 0.70 F10 (0.50) F10F2
SCHEMBL4420102 0.70 F10 (0.50) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1479675-A1 Indazole-derivatives as factor Xa inhibitors Aventis Pharma Deutschland GmbH (DE) 2004-11-24 EP disclosed