Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GPR6 | P46095 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879187 | 1.00 | KLK7 (0.52) | KLK7MCHR1ADRA2AMAPTTSHR | |
| SCHEMBL6465599 | 0.85 | MCHR1 (0.61) | KLK7MCHR1ADRA2AMAPTTSHR | |
| SCHEMBL6465595 | 0.85 | MCHR1 (0.61) | KLK7MCHR1ADRA2AMAPTTSHR | |
| SCHEMBL6467597 | 0.84 | MCHR1 (0.70) | KLK7MCHR1ADRA2AMAPTMEN1 | |
| SCHEMBL6467582 | 0.84 | MCHR1 (0.70) | KLK7MCHR1ADRA2AMAPTMEN1 | |
| SCHEMBL13794161 | 0.84 | MCHR1 (0.73) | KLK7MCHR1ADRA2ATSHRMAPK1 | |
| SCHEMBL27631432 | 0.82 | MCHR1 (0.48) | MCHR1ADRA2AMAPK1SMN1; SMN2 | |
| SCHEMBL6877534 | 0.81 | MCHR1 (0.53) | MCHR1ADRA2AMAPTRAB9ARXFP1 | |
| SCHEMBL6877538 | 0.81 | MCHR1 (0.53) | MCHR1ADRA2AMAPTRAB9ARXFP1 | |
| SCHEMBL6455698 | 0.81 | MCHR1 (0.49) | KLK7MCHR1ADRA2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |