Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 5/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | ACP1 | P24666 | 1/20 | 0.39 |
| ▸ | IGF1R | P08069 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6879539 | 1.00 | NPY5R (0.43) | NPY5RMCHR1ADRA2ATRPV1ACP1 | |
| SCHEMBL6867914 | 0.91 | ACP1 (0.44) | NPY5RMCHR1ADRA2ATRPV1ACP1 | |
| SCHEMBL6867920 | 0.91 | ACP1 (0.44) | NPY5RMCHR1ADRA2ATRPV1ACP1 | |
| SCHEMBL6868426 | 0.90 | MCHR1 (0.44) | NPY5RMCHR1ADRA2ATRPV1ACP1 | |
| SCHEMBL6868434 | 0.90 | MCHR1 (0.44) | NPY5RMCHR1ADRA2ATRPV1ACP1 | |
| SCHEMBL6464772 | 0.88 | MCHR1 (0.41) | NPY5RMCHR1ADRA2AACP1POLB | |
| SCHEMBL6459092 | 0.88 | MCHR1 (0.41) | NPY5RMCHR1ADRA2AACP1POLB | |
| SCHEMBL6878430 | 0.86 | NPY5R (0.43) | NPY5RMCHR1ADRA2APOLBACACB | |
| SCHEMBL6878437 | 0.86 | NPY5R (0.43) | NPY5RMCHR1ADRA2APOLBACACB | |
| SCHEMBL5526628 | 0.86 | MCHR1 (0.57) | NPY5RMCHR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |