Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.46 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880269 | 1.00 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6876757 | 0.91 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6868214 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6455511 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6466741 | 0.89 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6466734 | 0.89 | MCHR1 (0.51) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6873090 | 0.89 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6873084 | 0.89 | MCHR1 (0.47) | MCHR1ADRA2ANPY5RMEN1KMT2A | |
| SCHEMBL6868098 | 0.88 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RTSHRPKM | |
| SCHEMBL6868105 | 0.88 | MCHR1 (0.48) | MCHR1ADRA2ANPY5RTSHRPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |