Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 18/20 | 0.63 |
| ▸ | ADRA2A | P08913 | 10/20 | 0.63 |
| ▸ | HRH1 | P35367 | 6/20 | 0.56 |
| ▸ | HTR2B | P41595 | 5/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.56 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880399 | 1.00 | MCHR1 (0.63) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Hydrochloric Acid SCHEMBL7066307 | 0.99 | MCHR1 (0.62) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6464867 | 0.91 | MCHR1 (0.61) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6464872 | 0.91 | MCHR1 (0.61) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Hydrochloric Acid SCHEMBL6461653 | 0.90 | MCHR1 (0.60) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| Hydrochloric Acid SCHEMBL6461655 | 0.90 | MCHR1 (0.60) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6464615 | 0.89 | MCHR1 (0.76) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6464605 | 0.89 | MCHR1 (0.76) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6462094 | 0.89 | MCHR1 (0.61) | MCHR1ADRA2AHRH1HTR2BADRA1A | |
| SCHEMBL6462387 | 0.89 | MCHR1 (0.61) | MCHR1ADRA2AHRH1HTR2BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1464335-A2 | Quinoline, tetrahydroquinoline and pyrimidine derivatives as mch antagonist | Taisho Pharmaceutical Co. Ltd. (JP) | 2004-10-06 | — | — | EP | disclosed |