Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688038 | 0.95 | MEN1 (0.42) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL688349 | 0.94 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL688444 | 0.94 | MEN1 (0.43) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL687331 | 0.93 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL687120 | 0.93 | MEN1 (0.42) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL688313 | 0.92 | MEN1 (0.42) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL687806 | 0.92 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL688572 | 0.91 | MEN1 (0.47) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL688345 | 0.90 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL687363 | 0.89 | MEN1 (0.41) | MEN1KMT2AALDH1A1HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |