Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | BRS3 | P32247 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | PORCN | Q9H237 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6880986 | 1.00 | AOC3 (0.47) | AOC3CYP2D6CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL30639581 | 0.79 | CYP2C19 (0.49) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL31140242 | 0.79 | CYP2D6 (0.61) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL27032937 | 0.79 | CYP2C19 (0.49) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL13625688 | 0.78 | BRS3 (0.51) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL6880983 | 0.76 | CYP2D6 (0.47) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL6852314 | 0.76 | CYP2D6 (0.49) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL6854228 | 0.76 | CYP2D6 (0.49) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL7708187 | 0.75 | CYP2D6 (0.60) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 | |
| SCHEMBL21222736 | 0.75 | CYP2A6 (0.55) | CYP2D6CYP19A1CYP2C9CYP2C19BRS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825170-B2 | ERYTHROMYCIN TYPE MACROLIDE WITH A FUSED OXAZOLONE RING | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2004-11-30 | — | — | US | disclosed |
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | ORTHO-MCNEIL PHARMACEUTICAL, INC. | 2003-11-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220272-A1 | 6-O-acyl ketolide antibacterials | Q6ZSR9, ACSL6, RPS4Y1 | AOC3 1365/4885CYP2D6 125/4885CYP19A1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.