Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 19/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2353675 | 0.88 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL6881249 | 0.78 | HDAC6 (0.79) | HDAC6HDAC3HDAC1 | |
| SCHEMBL2225861 | 0.76 | HDAC6 (1.00) | HDAC6HDAC3HDAC1 | |
| SCHEMBL2357401 | 0.75 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL2227981 | 0.70 | HDAC6 (1.00) | HDAC6HDAC3HDAC1 | |
| SCHEMBL2227499 | 0.70 | HDAC6 (1.00) | HDAC6HDAC3HDAC1 | |
| SCHEMBL2223903 | 0.70 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL2225470 | 0.69 | HDAC6 (1.00) | HDAC6 | |
| SCHEMBL8641718 | 0.69 | HDAC6 (0.59) | HDAC6HDAC3HDAC1 | |
| SCHEMBL11210960 | 0.69 | HDAC6 (0.59) | HDAC6HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091213-A2 | REVERSE AMIDE COMPOUNDS AS PROTEIN DEACETYLASE INHIBITORS AND METHODS OF USE THEREOF | ACETYLON PHARMACEUTICALS (US) | 2011-07-28 | — | — | WO | disclosed |