Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.83 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | FAAH | O00519 | 1/20 | 0.67 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22508718 | 0.98 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL7037455 | 0.98 | TSHR (0.80) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL3594562 | 0.96 | MAPT (0.83) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL6687715 | 0.91 | TSHR (1.00) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL26092952 | 0.89 | TSHR (0.95) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL25702503 | 0.89 | TSHR (0.95) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL26094938 | 0.89 | TSHR (0.95) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL3459599 | 0.87 | SMN1; SMN2 (0.68) | TSHRSMN1; SMN2MAPTFAAHABCC4 | |
| SCHEMBL10898374 | 0.83 | TSHR (0.83) | TSHRSMN1; SMN2MAPTFAAHHPGD | |
| SCHEMBL1325279 | 0.83 | TSHR (0.83) | TSHRSMN1; SMN2MAPTFAAHHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6825269-B1 | POLYMER ACTIVATION WITH (N-HYDROXYCARBONYLOXY)-SUCCINIMIDE | DR. GOTTSCHALL INSTRUCTION GESELLSCHAFT FUER TECHNISCHE CHROMATOGRAFIE MBH (DE) | 2004-11-30 | — | — | US | disclosed |