⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1487946 | 1.00 | — | — | |
| SCHEMBL6881230 | 1.00 | — | — | |
| SCHEMBL13363826 | 0.93 | — | — | |
| SCHEMBL21376075 | 0.93 | — | — | |
| SCHEMBL2919671 | 0.93 | — | — | |
| SCHEMBL4371115 | 0.91 | CYP2D6 (0.47) | — | |
| SCHEMBL15743894 | 0.82 | — | — | |
| SCHEMBL12319243 | 0.82 | — | — | |
| SCHEMBL23066123 | 0.77 | CYP2D6 (0.38) | — | |
| SCHEMBL9550018 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116693439-A | Synthesis method of (R) -N-methyl-1- (pyrrolidine-2-yl) methylamine | 南通敏言生物医药科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-116693439-A | Synthesis method of (R) -N-methyl-1- (pyrrolidine-2-yl) methylamine | 南通敏言生物医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116693439-A | Synthesis method of (R) -N-methyl-1- (pyrrolidine-2-yl) methylamine | 南通敏言生物医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-116693439-A | Synthesis method of (R) -N-methyl-1- (pyrrolidine-2-yl) methylamine | 南通敏言生物医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-2560493-B1 | AN ENANTIOSELECTIVE PROCESS FOR CYCLOALKENYL B-SUBSTITUTED ALANINES | CHIRAL QUEST INC (US) | 2018-06-06 | — | — | EP | disclosed |
| EP-2486011-B1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | BRISTOL MYERS SQUIBB CO (US) | 2017-04-26 | — | — | EP | disclosed |
| US-8815869-B2 | Lactam acetamides as calcium channel blockers | ABBVIE INC. (US) | 2014-08-26 | — | — | US | disclosed |
| WO-2011044225-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2011-04-14 | — | — | WO | disclosed |