Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.54 |
| ▸ | PDE4D | Q08499 | 6/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.54 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883325 | 0.91 | PDE4A (0.53) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6886859 | 0.90 | PDE4A (0.59) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6882038 | 0.89 | PDE4D (0.48) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6887936 | 0.85 | PDE4A (0.49) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6882431 | 0.82 | PDE4A (0.52) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6882017 | 0.82 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL27657387 | 0.82 | PDE4A (0.56) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6881963 | 0.81 | PDE4A (0.51) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL6881958 | 0.81 | PDE4A (0.51) | PDE4APDE4DPDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL28062431 | 0.81 | PDE4D (0.57) | PDE4APDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0766671-B1 | TETRA-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH R&D LTD (GB) | 2004-09-29 | — | — | EP | claimed |