Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | MEN1 | O00255 | 3/20 | 0.81 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.81 |
| ▸ | HPGD | P15428 | 2/20 | 0.81 |
| ▸ | HTT | P42858 | 2/20 | 0.81 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.81 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.81 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.67 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL797563 | 0.90 | KDM4E (1.00) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL9920629 | 0.80 | PRKD1 (1.00) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL21724805 | 0.80 | PRKD1 (0.71) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL15472018 | 0.80 | KDM4E (0.84) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL9920628 | 0.80 | PRKD1 (0.71) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL15868699 | 0.80 | KDM4E (0.79) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL30897563 | 0.79 | MEN1 (0.69) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL4021839 | 0.77 | HSD17B10 (1.00) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL29666273 | 0.77 | HSD17B10 (1.00) | KDM4EMEN1KMT2AHPGDHTT | |
| SCHEMBL5239054 | 0.77 | HSD17B10 (0.93) | KDM4EMEN1KMT2AHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004098520-A2 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2004-11-18 | — | — | WO | claimed |
| US-4088647-A | Pyrazino (1,2,3-ab)-β-carboline derivatives and salts thereof and method of preparing same | GLUSHKOV ROBERT GEORGIEVICH | 1978-05-09 | — | — | US | disclosed |