Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CTSA | P10619 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | GCGR | P47871 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688336 | 0.93 | HPGD (0.38) | PTGER3MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL688270 | 0.88 | MEN1 (0.41) | PTGER3MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL688345 | 0.88 | MEN1 (0.41) | PTGER3MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL688307 | 0.88 | MEN1 (0.38) | PTGER3MEN1KMT2ACTSAMAPT | |
| SCHEMBL688349 | 0.87 | MEN1 (0.41) | PTGER3MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL688741 | 0.87 | SMN1; SMN2 (0.38) | PTGER3MEN1KMT2ACTSAMAPT | |
| SCHEMBL688444 | 0.87 | MEN1 (0.43) | PTGER3MEN1KMT2ACTSAMAPT | |
| SCHEMBL687676 | 0.87 | KMT2A (0.43) | PTGER3MEN1KMT2AMAPTRXFP1 | |
| SCHEMBL688166 | 0.87 | MEN1 (0.37) | PTGER3MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL688454 | 0.87 | MEN1 (0.41) | PTGER3MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1203766-B1 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | ENCYSIVE PHARMACEUTICALS INC (US) | 2012-02-29 | — | — | EP | disclosed |
| EP-1203766-A2 | Carboxylic acid derivatives that inhibit the binding of integrins to their receptors | TEXAS BIOTECHNOLOGY CORPORATION (US) | 2002-05-08 | — | — | EP | disclosed |