Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 18/20 | 0.79 |
| ▸ | SRC | P12931 | 16/20 | 0.79 |
| ▸ | TEK | Q02763 | 15/20 | 0.79 |
| ▸ | KDR | P35968 | 5/20 | 0.65 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.64 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.64 |
| ▸ | FYN | P06241 | 3/20 | 0.61 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.54 |
| ▸ | ERBB4 | Q15303 | 3/20 | 0.54 |
| ▸ | IGF1R | P08069 | 2/20 | 0.54 |
| ▸ | ERBB3 | P21860 | 2/20 | 0.54 |
| ▸ | PLK4 | O00444 | 1/20 | 0.54 |
| ▸ | AURKA | O14965 | 1/20 | 0.54 |
| ▸ | PAK4 | O96013 | 1/20 | 0.54 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.54 |
| ▸ | ABL1 | P00519 | 1/20 | 0.54 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.54 |
| ▸ | INSR | P06213 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6883639 | 1.00 | LCK (0.79) | LCKSRCTEKKDRLIMK1 | |
| Acetic Acid SCHEMBL6433384 | 0.97 | LCK (0.74) | LCKSRCTEKKDRLIMK1 | |
| Acetic Acid SCHEMBL6433394 | 0.97 | LCK (0.74) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6431132 | 0.93 | LCK (0.79) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6431127 | 0.93 | LCK (0.79) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6433392 | 0.91 | LCK (0.74) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6433390 | 0.91 | LCK (0.74) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL7702773 | 0.88 | SRC (1.00) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL7702761 | 0.88 | SRC (1.00) | LCKSRCTEKKDRLIMK1 | |
| SCHEMBL6431352 | 0.87 | SRC (1.00) | LCKSRCTEKKDRLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |