SCHEMBL6883837

SCHEMBL6883837

C1=CC(c2ccccc2)(c2ccccc2)C=C(c2ccccn2)N1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.39
LMNA P02545 3/20 0.39
CCR1 P32246 2/20 0.39
CCR5 P51681 2/20 0.39
CCR8 P51685 2/20 0.39
CYP1A2 P05177 1/20 0.39
POLB P06746 1/20 0.39
METAP1 P53582 1/20 0.39
BLM P54132 1/20 0.39
HIF1A Q16665 1/20 0.39
DOHH Q9BU89 1/20 0.39
P4HTM Q9NXG6 1/20 0.39
NPC1 O15118 6/20 0.36
RAB9A P51151 6/20 0.36
TP53 P04637 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
ALOX15 P16050 2/20 0.35
HTT P42858 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589588 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL15641196 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL435395 0.78 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL93597 0.76 KDM4E (0.42) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1311500 0.75 KDM4E (0.39) KDM4ELMNACCR1CCR5CCR8
SCHEMBL1312502 0.74 KDM4E (0.38) KDM4ELMNACCR1CCR5CCR8
SCHEMBL7054134 0.74 KDM4E (0.38) KDM4ELMNACCR1CCR5CCR8
SCHEMBL21518186 0.74 KDM4E (0.38) KDM4ELMNACCR1CCR5CCR8
SCHEMBL17912484 0.74 KDM4E (0.38) KDM4ELMNACCR1CCR5CCR8
SCHEMBL820253 0.74 KDM4E (0.38) KDM4ELMNACCR1CCR5CCR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114953672-A Wallboard and preparation process thereof 常州市贝美家居科技有限公司 2022-08-30 CN claimed
US-20210379087-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2021-12-09 US claimed
EP-3643305-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS Universität für Bodenkultur Wien (AT) 2020-04-29 EP claimed
EP-1196780-B1 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES PRESENS PREC SENSING GMBH (DE) 2004-10-06 EP claimed
US-6770220-B1 ACRYLONITRILE POLYMER AND COMPLEX COMPRISED OF RUTHENIUM, OSMIUM, RHENIUM, IRIDIUM, PLATINUM AND/OR PALLADIUM WITH MULTIDENTATE POLYPYRIDYL LIGANDS; INTERNAL STANDARD, MARKER; PROTECTED FROM INFLUENCE OF CHEMICAL AND BIOLOGICAL CONDITIONS PRESENS PRECISION SENSING GMBH (DE) 2004-08-03 US claimed
EP-1196780-A2 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES Presens Precision Sensing GmbH (DE) 2002-04-17 EP claimed
WO-2001006227-B1 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES PRESENS PREC SENSING GMBH (DE) 2001-08-16 WO claimed
WO-2001006227-A2 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES PRESENS PRECISION SENSING GMBH (DE) 2001-01-25 WO claimed
US-20260028667-A1 NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF SINGULAR GENOMICS SYSTEMS INC (US) 2026-01-29 US disclosed
CN-114953672-B Wallboard and preparation process thereof 常州市贝美家居科技有限公司 2023-06-09 CN disclosed
CN-115974935-A Ring metal organic rhodium complex of oxidized isoaporphine alkaloid and bipyridyl derivative and synthetic method and application thereof 广西师范大学 2023-04-18 CN disclosed
CN-114953672-A Wallboard and preparation process thereof 常州市贝美家居科技有限公司 2022-08-30 CN disclosed
US-20210379087-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2021-12-09 US disclosed
EP-3643305-A1 COMPOSITIONS FOR THE ELIMINATION OF SENESCENT CELLS Universität für Bodenkultur Wien (AT) 2020-04-29 EP disclosed
EP-1196780-B1 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES PRESENS PREC SENSING GMBH (DE) 2004-10-06 EP disclosed
US-6770220-B1 ACRYLONITRILE POLYMER AND COMPLEX COMPRISED OF RUTHENIUM, OSMIUM, RHENIUM, IRIDIUM, PLATINUM AND/OR PALLADIUM WITH MULTIDENTATE POLYPYRIDYL LIGANDS; INTERNAL STANDARD, MARKER; PROTECTED FROM INFLUENCE OF CHEMICAL AND BIOLOGICAL CONDITIONS PRESENS PRECISION SENSING GMBH (DE) 2004-08-03 US disclosed
EP-1196780-A2 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES Presens Precision Sensing GmbH (DE) 2002-04-17 EP disclosed
WO-2001006227-A2 PRODUCTION AND USE OF LUMINESCENT MICROPARTICLES AND NANOPARTICLES PRESENS PRECISION SENSING GMBH (DE) 2001-01-25 WO disclosed
EP-0583748-A1 Method for recovering oxygen from oxygen-containing gaseous mixtures AIR PRODUCTS AND CHEMICALS, INC. (US) 1994-02-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260028667-A1 NUCLEOTIDE CLEAVABLE LINKERS AND USES THEREOF POLN, NSUN2, POLL KDM4E 2845/4885LMNA 51/4885CCR1 1976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.