Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 12/20 | 0.33 |
| ▸ | CA2 | P00918 | 12/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 6/20 | 0.31 |
| ▸ | CA12 | O43570 | 5/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6888000 | 0.89 | MEN1 (0.35) | GSK3B | |
| SCHEMBL6885088 | 0.87 | GSK3B (0.36) | GSK3BCA1CA2ADKTSHR | |
| SCHEMBL6884989 | 0.87 | GSK3B (0.36) | GSK3BCA1CA2ADKTSHR | |
| SCHEMBL6885551 | 0.86 | GSK3B (0.36) | GSK3BCA1CA2ADKTSHR | |
| SCHEMBL6887384 | 0.86 | GSK3B (0.36) | GSK3BCA1CA2ADKTSHR | |
| SCHEMBL6887507 | 0.85 | GSK3B (0.44) | GSK3BCA1CA2ADKTSHR | |
| SCHEMBL6884779 | 0.84 | GSK3B (0.33) | GSK3BTSHR | |
| SCHEMBL6887576 | 0.84 | GSK3B (0.34) | GSK3BCA1CA2 | |
| SCHEMBL6882294 | 0.84 | GSK3B (0.34) | GSK3BCA1CA2 | |
| SCHEMBL6886842 | 0.83 | HDAC1 (0.35) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |