Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 5/20 | 0.58 |
| ▸ | CYP11B2 | P19099 | 8/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 7/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468334 | 0.81 | AR (0.54) | ARCYP11B2CYP11B1KDM4E | |
| SCHEMBL6890107 | 0.76 | AR (0.58) | ARCYP11B2CYP11B1CYP19A1APP | |
| SCHEMBL6469473 | 0.75 | AR (0.66) | ARCYP11B2CYP11B1CYP19A1APP | |
| SCHEMBL6465272 | 0.74 | AR (1.00) | ARCYP11B2CYP11B1CYP19A1ALDH1A1 | |
| SCHEMBL6469658 | 0.74 | AR (0.58) | ARCYP11B2CYP11B1CYP19A1CYP3A4 | |
| SCHEMBL6464828 | 0.73 | AR (0.77) | ARCYP11B2CYP11B1CYP19A1ALDH1A1 | |
| SCHEMBL6890606 | 0.70 | AR (0.52) | ARCYP11B2CYP11B1CYP19A1 | |
| SCHEMBL6464186 | 0.70 | AR (0.81) | ARCYP11B2CYP11B1ALDH1A1CYP3A4 | |
| SCHEMBL6464840 | 0.70 | AR (0.78) | ARCYP11B2CYP11B1 | |
| SCHEMBL6886740 | 0.69 | AR (0.52) | ARCYP11B2CYP11B1CYP19A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |