Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 3/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885248 | 1.00 | CYP4F2 (0.45) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6887506 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6887499 | 0.99 | CYP4F2 (0.44) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6888527 | 0.93 | CYP4F2 (0.41) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6888522 | 0.93 | CYP4F2 (0.41) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6886124 | 0.92 | PPARA (0.41) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6886116 | 0.92 | PPARA (0.41) | CYP4F2CYP4A11PPARAPPARGKDM4E | |
| SCHEMBL6156488 | 0.89 | PPARA (0.47) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6156496 | 0.89 | PPARA (0.47) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL6155173 | 0.88 | PPARA (0.48) | PPARAPPARGKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |