SCHEMBL6885376

SCHEMBL6885376

CC1(C)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.39

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL149624 1.00 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL297815 1.00 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL555525 1.00 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL2402774 0.95 MEN1 (0.36) MEN1KMT2ATDP1
SCHEMBL1280064 0.90 MEN1 (0.39) MEN1KMT2ATDP1
SCHEMBL3459462 0.89
SCHEMBL3459610 0.86 MEN1 (0.36) MEN1KMT2ATDP1
SCHEMBL17598855 0.84
SCHEMBL3459237 0.84 MEN1 (0.31) MEN1KMT2ATDP1
SCHEMBL3458492 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0693924-B1 METHODS FOR (IN VIVO) DELIVERY OF BIOLOGICS AND COMPOSITIONS USEFUL THEREFOR AMERICAN BIOSCIENCE INC (US) 2004-04-21 EP disclosed
US-5665382-A CROSSLINKING AND SULFIDING BIOCOMPATIBLE MATERIAL VIVORX PHARMACEUTICALS, INC. (US) 1997-09-09 US disclosed
US-5665383-A CROSSLINKING AND SULFIDING BIOCOMPATIBLE MATERIAL VIVORX PHARMACEUTICALS, INC. (US) 1997-09-09 US disclosed
EP-0693924-A4 METHODS FOR -i(IN VIVO) DELIVERY OF BIOLOGICS AND COMPOSITIONS USEFUL THEREFOR VIVORX PHARMACEUTICALS INC (US) 1997-08-06 EP disclosed
US-5650156-A ENCAPSULATION OF DRUGS, MICROPARTICLES, MICROEMULSIONS, SHELL CROSSLINKED BY DISULFIDE BONDS VIVORX PHARMACEUTICALS, INC. (US) 1997-07-22 US disclosed
US-5639473-A SUBJECTING AQUEOUS MEDIUM CONTAINING BIOCOMPATIBLE MATERIAL CAPABLE OF BEING CROSSLINKED BY DISULFIDE BONDS AND NUCLEIC ACID CONSTRUCT TO HIGH INTENSITY ULTRASOUND WAVES VIVORX PHARMACEUTICALS, INC. (US) 1997-06-17 US disclosed
US-5635207-A SUBJECTING AQUEOUS MEDIUM CONTAINING OXYGEN BINDING PROTEIN TO HIGH INTENSITY ULTRASOUND CONDITIONS TO PROMOTE CROSSLINKING AND FORM POLYMERIC SHELL OF SPECIFIED SIZE VIVORX PHARMACEUTICALS, INC. (US) 1997-06-03 US disclosed
US-5498421-A IN A POLYMERIC SHELL CONTAINING SULFHYDRYL AND/OR DISULFIDE GROUPS VIVORX PHARMACEUTICALS, INC. (US) 1996-03-12 US disclosed
EP-0693924-A1 METHODS FOR $i(IN VIVO) DELIVERY OF BIOLOGICS AND COMPOSITIONS USEFUL THEREFOR VIVORX PHARMACEUTICALS, INC. (US) 1996-01-31 EP disclosed
WO-1994018954-A1 METHODS FOR IN VIVO DELIVERY OF BIOLOGICS AND COMPOSITIONS USEFUL THEREFOR VIVORX PHARMACEUTICALS, INC. (US) 1994-09-01 WO disclosed