Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 10/20 | 0.58 |
| ▸ | LCK | P06239 | 7/20 | 0.58 |
| ▸ | TEK | Q02763 | 6/20 | 0.58 |
| ▸ | KDR | P35968 | 6/20 | 0.58 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.58 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.58 |
| ▸ | IGF1R | P08069 | 5/20 | 0.56 |
| ▸ | EGFR | P00533 | 9/20 | 0.53 |
| ▸ | ABL1 | P00519 | 7/20 | 0.53 |
| ▸ | ABL2 | P42684 | 7/20 | 0.53 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.52 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.52 |
| ▸ | LYN | P07948 | 3/20 | 0.51 |
| ▸ | INSR | P06213 | 2/20 | 0.51 |
| ▸ | CSF1R | P07333 | 2/20 | 0.51 |
| ▸ | RET | P07949 | 2/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | BLK | P51451 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2071754 | 0.98 | IGF1R (0.59) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL2074490 | 0.97 | SRC (0.61) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL6461905 | 0.91 | LCK (0.59) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL6461790 | 0.91 | SRC (0.59) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL2071878 | 0.89 | SRC (0.53) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL2072511 | 0.89 | IGF1R (0.59) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL2074582 | 0.89 | IGF1R (0.60) | SRCLCKTEKKDRLIMK1 | |
| Hydrochloric Acid SCHEMBL2071991 | 0.89 | SRC (0.52) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL6883793 | 0.88 | LCK (0.76) | SRCLCKTEKKDRLIMK1 | |
| SCHEMBL2074654 | 0.87 | IGF1R (0.60) | SRCLCKTEKKDRLIMK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |