Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1963074 | 0.82 | MEN1 (0.37) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL6884524 | 0.75 | MEN1 (0.35) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL6884925 | 0.75 | KMT2A (0.39) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL12070305 | 0.74 | MEN1 (0.35) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL13642116 | 0.73 | EPHX2 (0.39) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL15888154 | 0.71 | KMT2A (0.38) | KMT2AMEN1MAPK1HDAC4HDAC1 | |
| SCHEMBL6884521 | 0.69 | MEN1 (0.39) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL1964648 | 0.67 | MEN1 (0.38) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL6884817 | 0.67 | MEN1 (0.38) | KMT2AMEN1GAAMAPK1HDAC4 | |
| SCHEMBL13742611 | 0.66 | MEN1 (0.42) | KMT2AMEN1MAPK1HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011070541-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR UK LIMITED (GB) | 2011-06-16 | — | — | WO | disclosed |