Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 14/20 | 0.68 |
| ▸ | KDR | P35968 | 13/20 | 0.68 |
| ▸ | LCK | P06239 | 11/20 | 0.57 |
| ▸ | SRC | P12931 | 3/20 | 0.56 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 2/20 | 0.44 |
| ▸ | ABL2 | P42684 | 2/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6886516 | 0.85 | TEK (0.70) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2074411 | 0.84 | TEK (0.78) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2073373 | 0.84 | KDR (0.76) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2074902 | 0.82 | TEK (0.71) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2072170 | 0.81 | TEK (1.00) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2075180 | 0.81 | KDR (0.73) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2075821 | 0.81 | TEK (0.75) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2071955 | 0.80 | KDR (1.00) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2075883 | 0.78 | KDR (0.77) | TEKKDRLCKSRCPIK3CD | |
| SCHEMBL2074101 | 0.77 | TEK (0.81) | TEKKDRLCKSRCPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004100868-A2 | METHOD OF TREATING TRANSPLANT REJECTION | ABBOTT LABORATORIES (US) | 2004-11-25 | — | — | WO | disclosed |