SCHEMBL688696

SCHEMBL688696

Nc1ccc(Pc2ccc(N)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.57
MAPT P10636 2/20 0.57
KMT2A Q03164 2/20 0.57
CYP3A4 P08684 7/20 0.50
ALDH1A1 P00352 6/20 0.50
ALOX15 P16050 3/20 0.50
HSD17B10 Q99714 2/20 0.50
CA3 P07451 1/20 0.50
THRB P10828 1/20 0.50
CA6 P23280 1/20 0.50
CASP1 P29466 1/20 0.50
HIF1A Q16665 1/20 0.50
CA14 Q9ULX7 1/20 0.50
TDP1 Q9NUW8 7/20 0.47
TP53 P04637 2/20 0.47
MAPK1 P28482 4/20 0.42
ACHE P22303 1/20 0.42
TSHR P16473 4/20 0.40
APP P05067 3/20 0.40
GFER P55789 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9618210 0.88 TSHR (0.53) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL320609 0.76 MEN1 (1.00) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL27981 0.76
SCHEMBL20663055 0.73
SCHEMBL8389922 0.73
Fluoride SCHEMBL10704561 0.71 MEN1 (0.89) MEN1MAPTKMT2ACYP3A4ALDH1A1
Fluoride SCHEMBL20497199 0.71 MEN1 (0.89) MEN1MAPTKMT2ACYP3A4ALDH1A1
SCHEMBL21749649 0.71
SCHEMBL6537437 0.71
SCHEMBL1652426 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2726552-A2 POLYIMIDE-COATED FILLERS E. I. Du Pont de Nemours and Company (US) 2014-05-07 EP claimed
WO-2013003397-A2 POLYIMIDE-COATED FILLERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2013-01-03 WO claimed
EP-0712866-B1 Polymer scale deposition preventive agent SHINETSU CHEMICAL CO (JP) 1998-07-29 EP claimed
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
US-11851563-B2 Process and formulation for producing a polyamide having low caprolactam concentration and specific relative viscosity ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2023-12-26 US disclosed
CN-112585191-B Process and formulation for producing polyamides with low caprolactam concentration and specific relative viscosity 奥升德功能材料运营有限公司 2023-12-19 CN disclosed
CN-112601781-B Polyamide composition and plating application thereof 奥升德功能材料运营有限公司 2023-09-29 CN disclosed
CN-116209441-A Novel amine derivatives 住友制药株式会社 2023-06-02 CN disclosed
CN-112601782-B Polyamide composition and plating application thereof 奥升德功能材料运营有限公司 2023-04-07 CN disclosed
US-11345815-B2 Process and formulation for producing a polyamide having low caprolactam concentration and specific relative viscosity ASCEND PERFORMANCE MATERIALS OPERATIONS LLC (US) 2022-05-31 US disclosed
EP-3841150-A1 PROCESS AND FORMULATION FOR PRODUCING A POLYAMIDE HAVING LOW CAPROLACTAM CONCENTRATION AND SPECIFIC RELATIVE VISCOSITY Ascend Performance Materials Operations LLC (US) 2021-06-30 EP disclosed
EP-3455292-B1 POLYIMIDE COMPOSITIONS AND A POLYIMIDE TEST SOCKET HOUSING DU PONT (US) 2021-06-23 EP disclosed
US-4963645-A UNSATURATED END GROUPS UBE INDUSTRIES, LTD. (JP) 1990-10-16 US disclosed
US-4921745-A Honeycomb structure of aromatic polyimide UBE INDUSTRIES, LTD. (JP) 1990-05-01 US disclosed
US-4898753-A HAVING SURFACE PROTRUSIONS; COATING POLYIMIDE FILM WITH POLYAMIC SOLUTION CONTAINING SILICA, HEAT TREATMENT UBE INDUSTRIES, LTD. (JP) 1990-02-06 US disclosed
US-4869861-A Process for producing a shaped and drawn aromatic imide polymer article UBE INDUSTRIES, LTD. (JP) 1989-09-26 US disclosed
EP-0304913-A2 Terminal-modified imide oligomer and solution composition of the same UBE INDUSTRIES, LTD. (JP) 1989-03-01 EP disclosed
EP-0293904-A2 Antistatic aromatic polyimide article UBE INDUSTRIES, LTD. (JP) 1988-12-07 EP disclosed
US-4788098-A Aromatic polyimide laminate sheet UBE INDUSTRIES, INC. (JP) 1988-11-29 US disclosed
US-4411952-A DIRECT BONDING TO METALLIC FOILS UBE INDUSTRIES, LTD. (JP) 1983-10-25 US disclosed