SCHEMBL6887187

SCHEMBL6887187

Cc1cc(C2=Cc3ccccc3C2[Zr](C)(C)(C)(C)(=[SiH2])C2C(c3cc(C)cc4ccc5ccccc5c34)=Cc3ccccc32)c2c(ccc3ccccc32)c1

nearest known ligand 0.31

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2A6 P11509 1/20 0.31
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
TSHR P16473 1/20 0.30
MAPK1 P28482 1/20 0.30
CASP1 P29466 1/20 0.30
RAB9A P51151 1/20 0.30
CASP7 P55210 1/20 0.30
ATM Q13315 1/20 0.30
HIF1A Q16665 1/20 0.30
HSD17B10 Q99714 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6890204 0.89
SCHEMBL6895643 0.85 CYP1A2 (0.38) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL7643736 0.80 CYP1A2 (0.33) CYP1A2CYP2A6CYP3A4HPGDTSHR
SCHEMBL7808027 0.79 CYP1A2 (0.33) CYP1A2CYP2A6CYP3A4HPGDTSHR
Hydrochloric Acid SCHEMBL6894703 0.78 CYP1A2 (0.31) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL3115502 0.78 CYP1A2 (0.31) CYP1A2CYP2A6
SCHEMBL6893906 0.76 CYP1A2 (0.32) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL3115496 0.75 CYP1A2 (0.30) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL7140827 0.75 CYP1A2 (0.30) CYP1A2CYP2A6
Hydrochloric Acid SCHEMBL6885643 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6759500-B1 PRODUCING FIBERS, FILMS AND MOLDINGS, IN PARTICULAR FOR PRODUCING TUBES HAVING A HIGH CREEP RUPTURE STRENGTH UNDER INTERNAL PRESSURE BASELL POLYOLEFINE GMBH (DE) 2004-07-06 US disclosed
US-6506856-B2 Preparing polymers based on monomers having a C-C double and/or C-C triple bond by polymerization of these monomers in the presence of catalyst system comprising as active constituents a compound of an early transition metal BASF AKTIENGESELLSCHAFT (DE) 2003-01-14 US disclosed