Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPKAPK2 | P49137 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273746 | 0.86 | NR1H4 (0.53) | BAZ2BKDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL274833 | 0.78 | NR1H4 (0.53) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL273672 | 0.78 | NR1H4 (0.56) | BAZ2BKDM4EMAPTALOX15SMN1; SMN2 | |
| SCHEMBL274121 | 0.77 | NR1H4 (0.65) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL275044 | 0.75 | NR1H4 (0.65) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL274679 | 0.74 | NR1H4 (0.73) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL275249 | 0.74 | NR1H4 (0.61) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL275067 | 0.73 | NR1H4 (0.59) | KDM4EMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL273066 | 0.72 | NR1H4 (0.56) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 | |
| SCHEMBL273445 | 0.72 | PLK4 (0.49) | KDM4EMAPTALOX15SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532153-B1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X CEPTOR THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | claimed |