Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 12/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885832 | 1.00 | MRGPRX4 (0.42) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6885829 | 1.00 | MRGPRX4 (0.42) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6881292 | 0.91 | MRGPRX4 (0.41) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6881326 | 0.91 | MRGPRX4 (0.41) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6881296 | 0.91 | MRGPRX4 (0.41) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6154568 | 0.89 | NR4A2 (0.47) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6154817 | 0.89 | NR4A2 (0.47) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6154561 | 0.89 | NR4A2 (0.47) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6881445 | 0.86 | MRGPRX4 (0.43) | MRGPRX4NR4A1NR4A2NR4A3MAOB | |
| SCHEMBL6888607 | 0.86 | MRGPRX4 (0.43) | MRGPRX4NR4A1NR4A2NR4A3MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689922-B1 | BIAROMATIC COMPOUNDS WHICH ARE ANALOGUES OF VITAMIN D HAVE A MARKED ACTIVITY IN THE FIELDS OF CELL DIFFERENTIATION AND PROLIFERATION | GALDERMA RESEARCH & DEVELOPMENT S.N.C. (FR) | 2004-02-10 | — | — | US | disclosed |