Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.72 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887725 | 1.00 | AR (0.72) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL6469335 | 0.90 | AR (0.74) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL6469722 | 0.84 | AR (1.00) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL6469638 | 0.78 | AR (0.83) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL29071902 | 0.77 | AR (0.74) | ARLMNATSHRSMN1; SMN2MEN1 | |
| SCHEMBL6466355 | 0.77 | AR (1.00) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL29071900 | 0.74 | AR (0.70) | ARLMNATSHRSMN1; SMN2MEN1 | |
| SCHEMBL6466983 | 0.74 | AR (0.79) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL6469582 | 0.74 | AR (0.79) | ARPLA2G2ALMNATSHRSMN1; SMN2 | |
| SCHEMBL6469575 | 0.74 | AR (1.00) | ARPLA2G2ALMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |