Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5031873 | 0.90 | POLB (0.53) | HPGDMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL5037078 | 0.83 | HPGD (0.51) | HPGDMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL6426963 | 0.80 | PPARA (0.44) | HPGDLMNAHTTSMN1; SMN2 | |
| SCHEMBL5034531 | 0.79 | PPARA (0.41) | HPGDMAPTLMNAMEN1KMT2A | |
| SCHEMBL6888818 | 0.79 | HTT (0.43) | HPGDMAPTALDH1A1LMNAHTT | |
| SCHEMBL5034523 | 0.77 | HPGD (0.46) | HPGDMAPTALDH1A1NPSR1NPC1 | |
| SCHEMBL6427520 | 0.77 | PPARA (0.48) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6503265 | 0.77 | HPGD (0.56) | HPGDMAPTALDH1A1HSD17B10KDM4E | |
| SCHEMBL5032845 | 0.76 | PPARA (0.46) | LMNA | |
| SCHEMBL5029907 | 0.76 | PPARA (0.40) | HPGDALDH1A1LMNAHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1452521-A1 | CYCLIC COMPOUND AND PPAR AGONIST | Eisai Co., Ltd. (JP) | 2004-09-01 | — | — | EP | disclosed |