Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK2 | O00142 | 3/20 | 0.55 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.54 |
| ▸ | TYMP | P19971 | 12/20 | 0.53 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2578434 | 0.92 | TK2 (0.48) | TK2P2RY2TYMP | |
| SCHEMBL2583126 | 0.92 | TK2 (0.50) | TK2P2RY2TYMP | |
| SCHEMBL2575472 | 0.85 | TK2 (0.58) | TK2P2RY2TYMP | |
| SCHEMBL2579346 | 0.85 | TK2 (0.57) | TK2P2RY2TYMP | |
| SCHEMBL2578125 | 0.85 | TK2 (0.42) | TK2P2RY2TYMP | |
| SCHEMBL2586206 | 0.85 | TK2 (0.44) | TK2P2RY2TYMP | |
| SCHEMBL2589811 | 0.84 | TK2 (0.53) | TK2P2RY2TYMP | |
| SCHEMBL2580985 | 0.84 | TK2 (0.49) | TK2P2RY2TYMP | |
| SCHEMBL8535399 | 0.84 | TYMP (0.57) | TK2TYMP | |
| SCHEMBL9229284 | 0.84 | HSP90AA1 (0.60) | P2RY2TYMPP2RY6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1411954-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | Pharmasset Limited (BB) | 2004-04-28 | — | — | EP | disclosed |
| WO-2002032920-A2 | MODIFIED NUCLEOSIDES FOR TREATMENT OF VIRAL INFECTIONS AND ABNORMAL CELLULAR PROLIFERATION | PHARMASSET LIMITED (BB) | 2002-04-25 | — | — | WO | disclosed |