Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 20/20 | 0.53 |
| ▸ | CTRC | Q99895 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7931209 | 1.00 | F2 (0.53) | F2CTRCPRSS2 | |
| SCHEMBL6890605 | 0.90 | F2 (0.52) | F2CTRCPRSS2 | |
| SCHEMBL6747829 | 0.87 | F2 (0.69) | F2PRSS2 | |
| Hydrochloric Acid SCHEMBL6749357 | 0.86 | F2 (0.68) | F2PRSS2 | |
| SCHEMBL7931220 | 0.86 | F2 (0.44) | F2CTRCPRSS2 | |
| SCHEMBL7931212 | 0.80 | F2 (0.40) | F2CTRCPRSS2 | |
| SCHEMBL6747827 | 0.79 | F2 (0.51) | F2CTRCPRSS2 | |
| SCHEMBL6745960 | 0.78 | F2 (0.76) | F2PRSS2 | |
| SCHEMBL6745985 | 0.78 | F2 (0.73) | F2PRSS2 | |
| SCHEMBL6749901 | 0.78 | F2 (0.67) | F2PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6730783-B2 | REACTING AMINOGUANIDINE WITH CARBONYL COMPOUND TO FORM AMIDINOHYDRAZONE; REDUCTION; REACTING WITH ALKOXYAMINE; GUANIDINYLATION; ANTICOAGULANTS | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2004-05-04 | — | — | US | disclosed |