SCHEMBL6889017

SCHEMBL6889017

O=C(NCc1cccc(CN(CCc2nc3ccccc3[nH]2)C2CCCc3cccnc32)c1)c1ccncc1

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CXCR4 P61073 20/20 0.62
CHRM2 P08172 1/20 0.54
CYP2D6 P10635 1/20 0.54
DRD2 P14416 1/20 0.54
OPRM1 P35372 1/20 0.54
KCNH2 Q12809 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6885142 0.94 CXCR4 (0.61) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4066844 0.89 CXCR4 (0.59) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4064430 0.89 CXCR4 (0.60) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4063211 0.88 CXCR4 (0.69) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4066509 0.87 CXCR4 (0.58) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL6890383 0.87 CXCR4 (0.60) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4069490 0.86 CXCR4 (0.68) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4065649 0.86 CXCR4 (0.72) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL4062379 0.84 CXCR4 (0.58) CXCR4CHRM2CYP2D6DRD2OPRM1
SCHEMBL5055219 0.84 CXCR4 (0.67) CXCR4CHRM2CYP2D6DRD2OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6835731-B2 Viricides; antiinflammatory agents; antiallergens; antiarthritic agents ANORMED, INC. (CA) 2004-12-28 US disclosed