Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.60 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6890070 | 0.87 | AR (0.56) | ARPPARGKDM4EALDH1A1MEN1 | |
| SCHEMBL6468106 | 0.87 | AR (0.53) | ARPPARGALDH1A1MEN1KMT2A | |
| SCHEMBL2638817 | 0.86 | NOTUM (0.48) | ARKDM4EALDH1A1 | |
| SCHEMBL2637504 | 0.85 | HPGD (0.47) | ARKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL2637458 | 0.84 | NOTUM (0.43) | ARKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL15497073 | 0.83 | PTGDR2 (0.45) | KMT2A | |
| SCHEMBL1030435 | 0.79 | S1PR1 (0.43) | — | |
| SCHEMBL6883054 | 0.76 | MAPT (0.47) | ARALDH1A1MEN1KMT2A | |
| SCHEMBL6467007 | 0.75 | AR (0.51) | ARALDH1A1MEN1KMT2A | |
| SCHEMBL6469722 | 0.75 | AR (1.00) | ARKDM4EPLA2G2AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |