Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 13/20 | 0.72 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6464888 | 0.89 | AR (0.77) | ARPTGDR2CYP11B2TSHR | |
| SCHEMBL6469303 | 0.88 | AR (0.67) | ARTSHR | |
| SCHEMBL6469333 | 0.87 | AR (0.66) | ARPTGDR2 | |
| SCHEMBL6465272 | 0.84 | AR (1.00) | ARCYP11B2 | |
| SCHEMBL6464361 | 0.82 | AR (0.59) | ARLMNASMN1; SMN2 | |
| SCHEMBL6464828 | 0.81 | AR (0.77) | ARPTGDR2CYP11B2 | |
| SCHEMBL6466964 | 0.81 | AR (0.66) | ARPTGDR2FEN1LMNATSHR | |
| SCHEMBL6464186 | 0.77 | AR (0.81) | ARCYP11B2TSHR | |
| SCHEMBL6464840 | 0.77 | AR (0.78) | ARPTGDR2CYP11B2 | |
| SCHEMBL6468911 | 0.77 | AR (1.00) | ARLMNATSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | claimed |
| EP-1466902-A1 | ANDROGEN RECEPTOR ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2004-10-13 | — | — | EP | disclosed |