Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.87 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.87 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.87 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | MLYCD | O95822 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ACACB | O00763 | 1/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161880 | 0.87 | GAA (0.81) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL27727377 | 0.87 | GAA (0.87) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL12852589 | 0.84 | GAA (0.76) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL1753831 | 0.83 | KMT2A (0.81) | GAAKMT2AHSD17B10HDAC8HDAC6 | |
| SCHEMBL161881 | 0.83 | KMT2A (0.81) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL23665645 | 0.82 | KMT2A (0.78) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL7090374 | 0.82 | GAA (0.78) | GAAKMT2AHSD17B10HPGDPRMT5 | |
| SCHEMBL1196328 | 0.82 | GAA (0.78) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL31055430 | 0.82 | KMT2A (0.78) | GAAKMT2AHSD17B10HPGDATM | |
| SCHEMBL13981910 | 0.82 | KMT2A (0.78) | GAAKMT2AHSD17B10HDAC6HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004502669-A | — | — | 2004-01-29 | — | — | JP | claimed |
| EP-1353898-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | Elan Pharmaceuticals, Inc. (US) | 2003-10-22 | — | — | EP | claimed |
| WO-2002002512-A2 | COMPOUNDS TO TREAT ALZHEIMER'S DISEASE | ELAN PHARMACEUTICALS, INC. (US) | 2002-01-10 | — | — | WO | claimed |
| US-20230136349-A1 | CORE-SHELL DYE, PHOTOSENSITIVE RESIN COMPOSITION INCLUDING THE SAME, AND COLOR FILTER | SAMSUNG SDI CO., LTD. (KR) | 2023-05-04 | — | — | US | disclosed |