Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRACR2A | Q9BSW2 | 14/20 | 0.61 |
| ▸ | ORAI1 | Q96D31 | 4/20 | 0.55 |
| ▸ | KCNJ6 | P48051 | 2/20 | 0.47 |
| ▸ | KCNJ3 | P48549 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889816 | 0.84 | CRACR2A (0.58) | CRACR2AORAI1KCNJ6KCNJ3 | |
| SCHEMBL6890481 | 0.81 | CRACR2A (0.55) | CRACR2AORAI1KCNJ6KCNJ3 | |
| SCHEMBL1879356 | 0.78 | CRACR2A (0.72) | CRACR2AORAI1 | |
| SCHEMBL1667966 | 0.77 | CRACR2A (0.81) | CRACR2AORAI1KCNJ6KCNJ3 | |
| SCHEMBL20006441 | 0.76 | CRACR2A (0.58) | CRACR2AORAI1KCNJ6KCNJ3 | |
| SCHEMBL1668296 | 0.76 | CRACR2A (1.00) | CRACR2AORAI1 | |
| SCHEMBL1881601 | 0.76 | CRACR2A (1.00) | CRACR2AORAI1KCNJ6KCNJ3 | |
| SCHEMBL6887300 | 0.75 | CRACR2A (0.53) | CRACR2AORAI1KCNJ6KCNJ3 | |
| Hydrochloric Acid SCHEMBL1667869 | 0.75 | CRACR2A (0.98) | CRACR2AORAI1 | |
| SCHEMBL1886664 | 0.74 | CRACR2A (0.77) | CRACR2AORAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042797-A1 | PYRAZOLE DERIVATIVES AS MODULATORS OF CALCIUM RELEASE -ACTIVATED CALCIUM CHANNEL | ICOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-04-14 | — | — | WO | disclosed |