Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 9/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 8/20 | 0.56 |
| ▸ | ACACB | O00763 | 4/20 | 0.40 |
| ▸ | ACACA | Q13085 | 2/20 | 0.40 |
| ▸ | GBA1 | P04062 | 3/20 | 0.38 |
| ▸ | BTK | Q06187 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6889873 | 1.00 | ADORA1 (0.56) | ADORA1ADORA2AACACBACACAGBA1 | |
| SCHEMBL8355377 | 0.86 | ADORA1 (0.62) | ADORA1ADORA2A | |
| SCHEMBL4251034 | 0.75 | ADORA1 (0.87) | ADORA1ADORA2A | |
| SCHEMBL4251031 | 0.75 | ADORA1 (0.87) | ADORA1ADORA2A | |
| SCHEMBL4250345 | 0.74 | ADORA1 (0.56) | ADORA1ADORA2AACACBACACA | |
| SCHEMBL4496406 | 0.74 | ADORA1 (0.78) | ADORA1ADORA2A | |
| SCHEMBL15426758 | 0.73 | ADORA1 (0.77) | ADORA1ADORA2ABTK | |
| SCHEMBL4254159 | 0.72 | ADORA1 (0.66) | ADORA1ADORA2AGBA1 | |
| SCHEMBL15425807 | 0.72 | ADORA1 (0.81) | ADORA1ADORA2AGBA1 | |
| SCHEMBL15425805 | 0.72 | ADORA1 (0.70) | ADORA1ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6680324-B2 | 4-AMINO-6-PHENYL-PYRROLO(2,3-D)PYRIMIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2004-01-20 | — | — | US | disclosed |