Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 19/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL688051 | 0.94 | NR1H4 (0.55) | NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL688022 | 0.94 | NR1H4 (0.55) | NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL688906 | 0.93 | NR1H4 (0.54) | NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL687332 | 0.92 | NR1H4 (0.53) | NR1H4SMN1; SMN2 | |
| SCHEMBL689518 | 0.91 | NR1H4 (0.61) | NR1H4 | |
| SCHEMBL274423 | 0.90 | NR1H4 (0.69) | NR1H4 | |
| SCHEMBL689484 | 0.89 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL689489 | 0.88 | NR1H4 (0.51) | NR1H4ALDH1A1SMN1; SMN2 | |
| SCHEMBL688188 | 0.87 | NR1H4 (0.52) | NR1H4 | |
| SCHEMBL688945 | 0.87 | NR1H4 (0.57) | NR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532153-B1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X CEPTOR THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | claimed |