Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046979 | 0.85 | TYMP (0.45) | POLBNT5EABL1RIN1LMNA | |
| SCHEMBL6046965 | 0.83 | NT5E (0.40) | POLBNT5ELMNAMAPTALDH1A1 | |
| SCHEMBL6046977 | 0.81 | POLB (0.50) | POLBABL1RIN1LMNAMAPT | |
| SCHEMBL3626999 | 0.81 | POLB (0.56) | POLBADRB1DNMT1ABL1RIN1 | |
| SCHEMBL3627002 | 0.81 | POLB (0.56) | POLBADRB1DNMT1ABL1RIN1 | |
| SCHEMBL21011276 | 0.81 | POLB (0.56) | POLBADRB1DNMT1ABL1RIN1 | |
| SCHEMBL20346239 | 0.81 | POLB (0.56) | POLBADRB1DNMT1ABL1RIN1 | |
| SCHEMBL22942033 | 0.81 | POLB (0.56) | POLBADRB1DNMT1ABL1RIN1 | |
| SCHEMBL22625658 | 0.81 | POLB (0.53) | POLBADRB1DNMT1NT5EABL1 | |
| SCHEMBL21011163 | 0.80 | POLB (0.62) | POLBADRB1DNMT1NT5EABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212338-B1 | Nucleoside derivatives with photolabile protective groups | DEUTSCHES KREBSFORSCH (DE) | 2012-11-21 | — | — | EP | disclosed |
| US-6756492-B1 | Nucleoside derivatives with photo-unstable protective groups | DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUND DES OFFENTLICHEN RECHTS (DE) | 2004-06-29 | — | — | US | disclosed |