SCHEMBL68903

SCHEMBL68903

COC(=O)c1ccc2ncccc2c1C(=O)OC

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
MAP2K1 Q02750 1/20 0.54
HTT P42858 2/20 0.50
ALOX15 P16050 1/20 0.50
TSHR P16473 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 3/20 0.46
MAPK8 P45983 2/20 0.46
MAPK9 P45984 2/20 0.46
MAPK10 P53779 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
PSMD14 O00487 1/20 0.43
POLB P06746 2/20 0.42
LMNA P02545 1/20 0.42
GAA P10253 1/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
PKM P14618 1/20 0.42
ALDH1A1 P00352 1/20 0.42
HPGD P15428 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8657628 0.84 KDM4E (0.56) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL23660921 0.84 KDM4E (0.56) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL16914976 0.83 KDM4E (0.55) KDM4EMAP2K1HTTALOX15TSHR
SCHEMBL16915080 0.83 KDM4E (0.55) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL16915063 0.83 KDM4E (0.55) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL23724856 0.83 KDM4E (0.55) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL17442553 0.83 KDM4E (0.55) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL3984706 0.83 MEN1 (0.51) KDM4EMAP2K1HTTALOX15TSHR
SCHEMBL827213 0.81 KDM4E (0.59) KDM4EMAP2K1HTTALOX15MEN1
SCHEMBL23660926 0.80 KDM4E (0.51) KDM4EMAP2K1HTTALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed
US-5283335-A Controlling (mono or di)cotyledenous plants AMERICAN CYANAMID COMPANY (US) 1994-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885MAP2K1 2957/4885HTT 1871/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.