Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 20/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | PTAFR | P25105 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6892956 | 0.94 | GRM2 (0.68) | GRM2CYP3A4PTAFRHTR2B | |
| SCHEMBL6889558 | 0.91 | GRM2 (0.71) | GRM2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL1503212 | 0.89 | GRM2 (0.69) | GRM2CYP3A4 | |
| SCHEMBL6891870 | 0.87 | GRM2 (0.71) | GRM2CYP3A4 | |
| SCHEMBL6892635 | 0.87 | GRM2 (0.71) | GRM2CYP3A4PTAFRHTR2B | |
| SCHEMBL6891964 | 0.85 | GRM2 (0.73) | GRM2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL1503013 | 0.85 | GRM2 (0.69) | GRM2CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL1503304 | 0.85 | GRM2 (0.69) | GRM2CYP3A4 | |
| SCHEMBL6891418 | 0.84 | GRM2 (0.72) | GRM2CYP3A4PTAFRHTR2B | |
| SCHEMBL6891351 | 0.84 | GRM2 (0.77) | GRM2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011034741-A1 | IMIDAZOPYRIDIN-2-ONE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2011-03-24 | — | — | WO | disclosed |