Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | FABP3 | P05413 | 2/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | EDNRB | P24530 | 1/20 | 0.41 |
| ▸ | EDNRA | P25101 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885972 | 1.00 | TSHR (0.55) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL6890626 | 1.00 | TSHR (0.55) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL6890624 | 1.00 | TSHR (0.55) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL15116650 | 0.89 | TSHR (0.52) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL613562 | 0.88 | TSHR (0.49) | TSHRUSP2ALDH1A1KMT2AMEN1 | |
| SCHEMBL20054279 | 0.87 | TSHR (0.51) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL12330316 | 0.87 | TSHR (0.54) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL15125206 | 0.87 | TSHR (0.51) | TSHRFABP5USP2ALDH1A1KMT2A | |
| SCHEMBL9715115 | 0.85 | MAPK1 (0.50) | TSHRUSP2MAPTMAPK1 | |
| SCHEMBL15113828 | 0.85 | TSHR (0.49) | TSHRUSP2ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108484538-B | Synthesis method of nematicide containing lactone ring | 山东省联合农药工业有限公司 | 2020-06-12 | — | — | CN | claimed |
| CN-107011301-B | A kind of 2-(2- methoxyphenyl) -5- oxo-tetrahydrofuran -3- carboxylic acid preparation method | 山东省联合农药工业有限公司 | 2019-06-28 | — | — | CN | claimed |
| CN-108484538-A | A kind of synthetic method of the nematicide containing lactonic ring | 山东省联合农药工业有限公司 | 2018-09-04 | — | — | CN | claimed |
| CN-107011301-A | One kind 2（2 methoxyphenyls）The preparation method of the carboxylic acid of 5 oxo-tetrahydrofuran 3 | 山东省联合农药工业有限公司 | 2017-08-04 | — | — | CN | claimed |
| CN-108484538-B | Synthesis method of nematicide containing lactone ring | 山东省联合农药工业有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-108484538-B | Synthesis method of nematicide containing lactone ring | 山东省联合农药工业有限公司 | 2020-06-12 | — | — | CN | disclosed |
| CN-111162313-A | Polymer electrolyte and lithium ion battery | 珠海冠宇电池有限公司 | 2020-05-15 | — | — | CN | disclosed |
| CN-111146496-A | Polymer electrolyte and lithium ion battery containing same | 珠海冠宇电池有限公司 | 2020-05-12 | — | — | CN | disclosed |
| CN-107011301-B | A kind of 2-(2- methoxyphenyl) -5- oxo-tetrahydrofuran -3- carboxylic acid preparation method | 山东省联合农药工业有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-107011301-B | A kind of 2-(2- methoxyphenyl) -5- oxo-tetrahydrofuran -3- carboxylic acid preparation method | 山东省联合农药工业有限公司 | 2019-06-28 | — | — | CN | disclosed |
| CN-108484538-A | A kind of synthetic method of the nematicide containing lactonic ring | 山东省联合农药工业有限公司 | 2018-09-04 | — | — | CN | disclosed |
| CN-107011301-A | One kind 2（2 methoxyphenyls）The preparation method of the carboxylic acid of 5 oxo-tetrahydrofuran 3 | 山东省联合农药工业有限公司 | 2017-08-04 | — | — | CN | disclosed |
| US-4895963-A | THROMBOXANE A2 ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-01-23 | — | — | US | disclosed |
| US-4775685-A | THROMBOXANE A-2 ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-04 | — | — | US | disclosed |
| US-4775684-A | 1,3-dioxane ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-10-04 | — | — | US | disclosed |
| US-4723037-A | THROMBOXANE ANTAGONISTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-02 | — | — | US | disclosed |
| EP-0202086-A2 | Hexenoic acids | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-20 | — | — | EP | disclosed |
| EP-0201351-A2 | 1,3-Dioxane ethers | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-12 | — | — | EP | disclosed |
| EP-0201354-A2 | 2,4-Diphenyl-1,3-Dioxanes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-11-12 | — | — | EP | disclosed |
| EP-0142323-A2 | Process for making erythro-dihydroxyalkenoic acide derivatives | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-05-22 | — | — | EP | disclosed |