⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL607855 | 0.81 | TSHR (0.35) | — | |
| SCHEMBL12306268 | 0.77 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL19500209 | 0.77 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL72027 | 0.77 | — | — | |
| SCHEMBL19500205 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL12306238 | 0.75 | TSHR (0.42) | — | |
| SCHEMBL344277 | 0.75 | — | — | |
| SCHEMBL6100865 | 0.73 | HCAR2 (0.32) | — | |
| SCHEMBL12306266 | 0.73 | CA1 (0.37) | — | |
| SCHEMBL18856289 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677331-B2 | HAVING SUBSTITUTED IMIDAZO(5,1-B)THIAZOLE GROUP AT 2-POSITION; MICROBIOCIDES AGAINST BETA-LACTAMASE PRODUCING BACTERIA AND RESISTANT PSEUDOMONAS | MEIJI SEIKA KAISHA, LTD. (JP) | 2004-01-13 | — | — | US | disclosed |
| US-20030149016-A1 | Novel carbapenem derivatives | KANO YUKO (JP) | 2003-08-07 | — | — | US | disclosed |
| EP-1101766-A1 | NOVEL CARBAPENEM DERIVATIVES | MEIJI SEIKA KAISHA LTD. (JP) | 2001-05-23 | — | — | EP | disclosed |