Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 4/20 | 0.41 |
| ▸ | P2RY6 | Q15077 | 8/20 | 0.37 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 1/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 6/20 | 0.37 |
| ▸ | P2RY4 | P51582 | 5/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6046959 | 0.88 | POLB (0.42) | TYMPNPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL9126502 | 0.78 | P2RY6 (0.45) | TYMPP2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL6046979 | 0.78 | TYMP (0.45) | TYMPP2RY6P2RY14NT5ENPC1 | |
| SCHEMBL6046977 | 0.75 | POLB (0.50) | ALDH1A1 | |
| SCHEMBL6046965 | 0.75 | NT5E (0.40) | P2RY6NT5EP2RY2P2RY4ALDH1A1 | |
| SCHEMBL9230969 | 0.75 | P2RY6 (0.41) | TYMPP2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL27041199 | 0.75 | TYMP (0.49) | TYMPP2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL30274828 | 0.75 | TYMP (0.49) | TYMPP2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL27041194 | 0.75 | TYMP (0.49) | TYMPP2RY6P2RY14NT5EP2RY2 | |
| SCHEMBL17090823 | 0.75 | TYMP (0.51) | TYMPP2RY6P2RY14NT5EP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1438322-A2 | METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES | Chemogenix GmbH (DE) | 2004-07-21 | — | — | EP | disclosed |
| WO-2003035664-A2 | METHOD FOR COVALENTLY ATTACHING NUCLEOSIDES AND/OR NUCLEOTIDES ON SURFACES AND METHOD FOR DETERMINING COUPLING YIELDS IN THE SYNTHESIS OF NUCLEOTIDES | CHEMOGENIX GMBH (DE) | 2003-05-01 | — | — | WO | disclosed |