Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 7/20 | 0.74 |
| ▸ | HBB | P68871 | 2/20 | 0.74 |
| ▸ | BLM | P54132 | 2/20 | 0.74 |
| ▸ | USP2 | O75604 | 1/20 | 0.74 |
| ▸ | TSHR | P16473 | 1/20 | 0.74 |
| ▸ | EDNRA | P25101 | 1/20 | 0.74 |
| ▸ | HTR2A | P28223 | 1/20 | 0.74 |
| ▸ | RECQL | P46063 | 1/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.74 |
| ▸ | HPRT1 | P00492 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | POLG | P54098 | 1/20 | 0.55 |
| ▸ | TK1 | P04183 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acyclovir SCHEMBL18529423 | 0.99 | PNP (0.73) | PNPHBBBLMUSP2TSHR | |
| Palmitic Acid SCHEMBL18529399 | 0.99 | PNP (0.73) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL2817609 | 0.97 | PNP (0.76) | PNPHBBBLMUSP2TSHR | |
| Oleic Acid SCHEMBL1230441 | 0.94 | PNP (0.66) | PNPHBBBLMUSP2TSHR | |
| Oleic Acid SCHEMBL1230444 | 0.94 | PNP (0.66) | PNPHBBBLMUSP2TSHR | |
| Elaidic Acid SCHEMBL1230565 | 0.94 | PNP (0.66) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL20567690 | 0.93 | PNP (0.79) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL28448833 | 0.93 | PNP (0.83) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL9224824 | 0.91 | PNP (0.86) | PNPHBBBLMUSP2TSHR | |
| Acyclovir SCHEMBL9479083 | 0.88 | PNP (0.93) | PNPHBBBLMUSP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012110672-A1 | PHARMACEUTICAL COMPOSITION OF ACYCLOVIR PRODRUGS FOR TOPICAL USE | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2012-08-23 | — | — | WO | disclosed |
| WO-2012110672-A1 | PHARMACEUTICAL COMPOSITION OF ACYCLOVIR PRODRUGS FOR TOPICAL USE | UNIVERSIDAD COMPLUTENSE DE MADRID (ES) | 2012-08-23 | — | — | WO | disclosed |
| EP-2184286-B1 | Process for the manufacture of acyclovir pro-drugs | COGNIS IP MAN GMBH (DE) | 2012-02-29 | — | — | EP | disclosed |
| EP-2184286-A1 | Process for the manufacture of acyclovir pro-drugs | Cognis IP Management GmbH (DE) | 2010-05-12 | — | — | EP | disclosed |