Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL28966021 | 0.93 | TDP1 (0.71) | — | |
| Propylene Glycol SCHEMBL27919821 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL11357578 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL10346057 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL8092591 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL10380738 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL11361874 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL11356162 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL22401395 | 0.92 | — | — | |
| Propylene Glycol SCHEMBL11598351 | 0.92 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6797054-B2 | CEMENT SLURRY FOAMING AND STABILIZING ADDITIVES; BIODEGRADATION | HALLIBURTON ENERGY SERVICES, INC. | 2004-09-28 | — | — | US | claimed |
| CN-118084796-A | Imidazole derivatives and uses thereof | 远大医学营养科学(武汉)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118084797-A | Process for preparing imidazole derivatives | 远大医学营养科学(武汉)有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-118063389-A | Process for preparing imidazole derivatives | 远大医学营养科学(武汉)有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-112624928-B | Anticoagulant peach blossom effective component and application thereof | 黄河科技学院 | 2023-03-17 | — | — | CN | disclosed |
| CN-112538016-B | Method for extracting chlorogenic acid n-butyl ester from peach blossom | 黄河科技学院 | 2023-03-10 | — | — | CN | disclosed |
| CN-109212120-B | Method for constructing characteristic spectrum of medicinal evodia fruit and method for detecting quality of medicinal evodia fruit | 湖南省中医药研究院 | 2021-10-26 | — | — | CN | disclosed |
| CN-108884093-A | 6,7,8,9- tetrahydro -5H- pyrido [2,3-d] azepine * dopamine D 3 ligands | 辉瑞公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-104337760-B | A kind of Maxamine injection and preparation method thereof | 山东新时代药业有限公司 | 2018-09-04 | — | — | CN | disclosed |
| US-5968486-A | HYDROGEN PEROXIDE AND A-OLEFIN SULFONATE; SHAMPOO; BLEACHING | HELENE CURTIS, INC. (US) | 1999-10-19 | — | — | US | disclosed |
| US-4777038-A | NONIONIC, STORAGE-STABLE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1988-10-11 | — | — | US | disclosed |