Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 20/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.51 |
| ▸ | PGR | P06401 | 1/20 | 0.51 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL273597 | 0.88 | NR1H4 (0.80) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL3728500 | 0.86 | NR1H4 (0.80) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL10289869 | 0.85 | NR1H4 (0.58) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL13258940 | 0.84 | NR1H4 (0.82) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL13258943 | 0.81 | NR1H4 (0.60) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL4529631 | 0.81 | NR1H4 (0.59) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL13284308 | 0.80 | NR1H4 (0.52) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL4519777 | 0.79 | NR1H4 (0.59) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL688553 | 0.78 | NR1H4 (0.60) | NR1H4ESR1NR3C1PGRNR3C2 | |
| SCHEMBL4524962 | 0.77 | NR1H4 (0.61) | NR1H4ESR1NR3C1PGRNR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532153-B1 | AZEPINOINDOLE AND PYRIDOINDOLE DERIVATIVES AS PHARMACEUTICAL AGENTS | X CEPTOR THERAPEUTICS INC (US) | 2012-02-29 | — | — | EP | claimed |