Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRAS | P01112 | 12/20 | 0.61 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6887268 | 0.91 | HRAS (0.73) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6888472 | 0.89 | HRAS (0.73) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6890313 | 0.86 | HRAS (0.58) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6888575 | 0.84 | HRAS (0.64) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6888486 | 0.83 | HRAS (0.72) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL8590786 | 0.83 | HRAS (0.55) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6891481 | 0.83 | HRAS (0.55) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6888618 | 0.83 | HRAS (0.73) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL6890315 | 0.81 | HRAS (0.60) | HRASFNTAFNTBMMEECE1 | |
| SCHEMBL7953187 | 0.81 | HRAS (0.58) | HRASFNTAFNTBLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6737410-B1 | SMOOTH MUSCLE ANTIPROLIFERATION AGENTS; SUCH AS 1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-METHYL-CARBAMOYL)-2 -(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2004-05-18 | — | — | US | disclosed |
| US-6265382-B1 | E.G., (S--(R*, R*))-(1-((2-(4-BENZYLOXY-PHENYL)-1-PHENETHYLCARBAMOYL-ETHYL)-M ETHYL-CARBAM OYL)-2-(1H-IMIDAZOL-4-YL)-ETHYL)-CARBAMIC ACID BENZYL ESTER | WARNER-LAMBERT COMPANY | 2001-07-24 | — | — | US | disclosed |